Huggins Lab

Rational approaches to improving selectivity in drug design.

Submitted by chp4012 on April 28, 2021 - 2:41pm
TitleRational approaches to improving selectivity in drug design.
Publication TypeJournal Article
Year of Publication2012
AuthorsHuggins DJ, Sherman W, Tidor B
JournalJ Med Chem
Volume55
Issue4
Pagination1424-44
Date Published2012 Feb 23
ISSN1520-4804
KeywordsAllosteric Site, Drug Design, Models, Molecular, Molecular Conformation, Pharmaceutical Preparations, Protein Binding, Proteins, Static Electricity, Structure-Activity Relationship, Thermodynamics, Water
DOI10.1021/jm2010332
Alternate JournalJ Med Chem
PubMed ID22239221
PubMed Central IDPMC3285144
Grant ListT32 GM008334 / GM / NIGMS NIH HHS / United States
R56 GM065418 / GM / NIGMS NIH HHS / United States
R01 GM082209 / GM / NIGMS NIH HHS / United States
GM065418 / GM / NIGMS NIH HHS / United States
R01 GM065418 / GM / NIGMS NIH HHS / United States
GM082209 / GM / NIGMS NIH HHS / United States